保留胃窦空肠间置双通道手术与传统消化道重建对胃食管结合部癌患者生存质量及预后的影响对比

摘要

Objective: To explore the influence on prognosis and life quality for patients with gastroe-sophageal junction cancer by retained gastric antrum jejunal interposition dual channel operation and tradi-tional digestive tract reconstuction.Method: From Mar.2010 to Mar.2011, 92 cases were selected.They were divided into observation group (46 cases) and control group (46 cases) according to table of digital method.The control group underwent traditional digestive tract reconstruction, while the observation group a-dopted retained gastric antrum jejunal interposition dual channel operation.And then compared the life quali-ty, index of related operation and the survial rate of one and three years.Result: The life quality was im-proved 6 months after operation in both groups, but the score of daily life, health grade and the score of life quality were all superior to those in control group.There's significant difference ( P<0.05) .There's no signif-icant difference in operation time, blood loss during operation and hospital stay and incidence of complica-tions ( P>0.05) .There's no difference in survival rate of one to three years ( P>0.05) .Conclusion:It can improve the life quality and prognosis for the patients with retained gastric antrum jejunal interposition dual channel operation.It's worthy applying.%目的：研究对比保留胃窦空肠间置双通道手术与传统消化道重建对胃食管结合部癌（ GJC）患者生存质量及预后的影响。方法：选择2010年3月至2011年3月接受手术治疗的GJC患者92例作为研究对象。根据数字法随机分成观察组（46例）及对照组（46例）。对照组实施传统的消化道重建手术，观察组则实施保留胃窦空肠间置双通道手术，对比两组的生存质量，手术相关指标以及两组1年和3年的生存率情况。结果：两组手术6个月后的生存质量均有明显改善，但观察组在手术后6个月的日常生活评分、健康评分以及生存质量总评分等方面显著高于对照组，差异均有统计学意义（均P＜0．05）。两组在手术时间及术中出血量，以及住院时间和并发症发生率等方面相比，差异均无统计学意义（均P＞0．05）。两组在1年生存率及3年生存率方面对比，差异均无统计学意义（均P＞0．05）。结论：对GJC患者实施保留胃窦空肠间置双通道手术，可较好地改善患者的生存质量，促进患者获得积极预后，效果显著，值得临床推广。