应用ET技术评价高血压病患者早期颈动脉弹性功能的意义

摘要

目的:探讨血管跟踪技术(Echo-tracking, ET)评价高血压病患者早期颈动脉血管弹性的应用价值.方法:高血压患者78例,根据颈动脉内-中膜厚度(IMT)分为两组,A 组(n=36):IMT≤1. 0mm,B组(n=42):IMT>1.0mm,正常对照组75例健康人.应用 ET 检测三组人群的颈动脉硬化参数,包括弹性系数(Ep)、僵硬度(β)、顺应性(AC),通过观察这些参数的变化,评估高血压患者颈动脉弹性功能.结果:A组和B组的Ep、β 值均高于对照组,有显著性差异;A组和B 组的AC 值低于对照组,亦有显著性差异.B 组的 Ep、β 值高于 A 组,两组比较有显著性差异,而 AC 值低于 A 组,并有显著性差异.结论:高血压病患者的颈动脉弹性功能采用 ET 技术进行检测,可以准确的定量评价颈总动脉弹性,反应高血压病患者血管内皮功能受损情况,对临床及早采取相应干预措施,为高血压患者血管并发症的早期预测提供了实用、简便而客观的方法.%Objective:To explore value of E-tracking(ET) technology in evaluating the carotid elastic-ity in hypertensive patients. Methods: Seventy-eight hypertensive patients were divided into two groups ac-cording to the intima-media thickness(IMT)of carotid artery, group A (36 cases): IMT≤1.0mm, group B (42 cases):IMT>1.0mm,and normal control group (75 cases). Using ET technology to track the movement of common carotid arterial wall and measure the parameters: stiffness parameters (β), elastic coefficient (Ep),and arterial compliance(AC). Results:The values of Ep and β in group A and group B were signifi-cantly higher than those in control group. The AC values in group A and group B were lower than those in con-trol group,and there were also significant differences. The values of Ep and β in group B were higher than those in group A,there was a significant difference between the two groups,while the AC value was lower than that in group A,with significant difference. Conclusions: ET technology can reflect the vascular endothelial function earlier. It is a simple and useful method in evaluating the vascular changes of hypertensive patients.