Objective To explore the effect of music therapy combined with routine westem medicine on unstable angina. Methods One hundred twenty - two patients with unstable angina were randomly divided into music treatment group and control group, 61 patients in each group. Treatment group was given music therapy on the basis of routine western medicine. The two groups were compared with clinical symptoms, ECG performance, heart rate variability and biochemical indicators after two weeks. Results The improvements of angina pectoris and ECG in treatment group were better than those in the control group ( P ＜ 0.05 ). There were significant differences between two groups on references indexes of heart rate variability among SDNN, SDANN, RMSSD and pNN50 within 24 h ( P ＜0.01 ). There was obvious difference between two groups on the standard deviation of the average among continuously 5min segment oardiac within 24 h ( P ＜ 0.05 ). There were significant differences between two groups on the clinical and biochemical indicators of fibrinogen, plasma viscosity and serum creatinine after treatment ( P ＜ 0. 01 ). Total exercise time and ST segment depression rate of Treadmill test in the treatment group were significantly changed in comparison with those in control group after treatment ( P ＜ 0. 05 ). Conclusion The music therapy can improve the symptoms and related supplementary tests of the patients with unstable angina.%目的 观察常规西医配合音乐疗法治疗不稳定型心绞痛的临床疗效.方法 将122例不稳定型心绞痛患者随机分为干预组和对照组,各61例.对照组子常规西医治疗,干预组在对照组治疗基础上予播放音乐.2组均7 d为1个疗程,2个疗程后观察心绞痛疗效、心电图疗效、心率变异性、生化指标及临床运动平板试验检查结果.结果 干预组心绞痛疗效、心电图疗效均优于对照组(P<0.05);2 组治疗后心率变异性参考指标24 h内全部正常心搏间的标准差(SDNN)、24 h内连续5 min节段平均正常心搏问的标准差(SDANN)、相邻正常心搏间差值均方的平方根(RMSSD)、一定时间内相邻两正常心搏间差值>50 ms的个数所占该时间总心搏数的百分比(pNN50)及24 h内连续5 min节段心搏间的标准差平均值(SDNNindex)比较差异均有统计学意义(P<0.01,P<0.05);干预组治疗后纤维蛋白原、血浆黏度及血清肌酐(Cr)与本组治疗前比较差异均有统计学意义(P<0.05),2 组治疗后比较差异均有统计学意义(P<0.01);干预组治疗后运动平板试验总运动时间及ST段下移幅度与本组治疗前比较差异有统计学意义(P<0.05),2 组治疗后比较差异有统计学意义(P<0.05).结论 音乐疗法能明显改善不稳定型心绞痛患者的临床症状和相关的辅助检查.
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