含氟化疗方案治疗晚期胃癌的临床观察

摘要

目的：比较SC、XP、FOLFOX、CF、DCF等化疗方案治疗晚期胃癌的效果。方法回顾分析48例分别采用SC、XP、FOLFOX、CF及DCF多种治疗方案的初治晚期胃癌患者：采用方案根据患者的一般情况、经济条件或者患者从上级医院带来的方案。每28天为1个疗程，完成2个周期的化疗后，评估患者的近期疗效和毒副反应。结果含氟方案总的近期疗效54.1%。常见的不良反应为血液学毒性，恶心呕吐，肌肉酸痛，疲乏，脱发，患者均基本可耐受。结论晚期胃癌患者应用含氟方案近期疗效较好，不良反应可以耐受，值得临床参考。%Objective Comparing different chemotherapy regimen SC, XP, FOLFOX, CF, DCF model, such as chemotherapy regimens for the treatment of advanced gastric cancer. Methods Retrospective analysis of 48 cases with SC, XP, FOLFOX, CF and DCF model a variety of early treatment of patients with advanced gastric cancer:Using scheme according to the patient's general condition ,economic conditions or brought from the superior hospital patients with solution. The cycle of the chemotherapy was 28 days was given for 2cycles Evaluate the recent curative effect and adverse reaction of patients. Results The total effective rate (CR+PR) was 54.1%. Common adverse events were hematological toxicity, nausea, vomiting, muscle aches, fatigue, hair loss. The adverse reactions are well tolerated. Conclusion Containing lfuorouracil scheme chemotherapy for advanced gastric cancer can improve the curative effect, reduce the chemotherapy reaction, and improve the quality of life. Is worth for clinical reference.