剥脱性龈炎患者的临床牙周状况及相关因素分析

摘要

目的 研究剥脱性龈炎患者的临床牙周状况,探讨影响其牙周健康的临床指标的相关因素.方法 采用立意抽样,选择42例剥脱性龈炎患者为病例组,病例组经组织学和直接免疫荧光检测,25例诊断为口腔扁平苔藓(oral lichen planus,OLP)(OLP组),17例诊断为口腔黏膜良性类天疱疮(mucous membrane pemphigoid,MMP)(MMP组).以剥脱性龈炎患者的健康家属为对照组,检测牙周临床指标并进行相关因素分析.结果 剥脱性龈炎患者就诊以中年女性居多.OLP组、MMP组在探诊深度、临床附着水平和探诊出血阳性率方面均显著高于对照组:OLP组探诊深度(χ2=53.058,P<0.001)、临床附着水平(χ2=30.292,P<0.001)和探诊出血阳性率(χ2=50.003,P<0.001)高于对照组;MMP组探诊深度(χ2=32.989,P<0.001)、临床附着水平(χ2=32.470,P<0.001)和探诊出血阳性率(χ2=36.236,P<0.001)高于对照组.剥脱性龈炎病例发病至就诊的时间与探诊深度(rs=0.523,P<0.001)和探诊出血阳性率(rs=0.377,P=0.014)之间存在相关关系.结论 剥脱性龈炎患者牙周病变程度更重,需要对此类患者进行早期治疗.%Objective To study the clinical periodontal status of patients with desquamative gingivitis (DG) and an-alyze the factors that influence clinical periodontal indicators. Methods A purposive sampling method was used to ob-tain 42 subjects for a DG case group and a control group. Periodontal clinical indicators were detected, and related fac-tors were analyzed. Results The DG patients were primarily middle-aged women. Periodontal clinical indicators were more prevalent in individuals with oral lichen planus (OLP) and mucous membrane pemphigoid (MMP) than in the con-trol group. Probing depth (PD) (χ2=53.058, P<0.001;χ2=32.989, P<0.001), clinical attachment (χ2=30.292, P<0.001;χ2=32.470, P<0.001) and the positive rate of bleeding on probing (BOP) (χ2=50.003, P<0.001;χ2=36.236, P<0.001) were higher in the OLP and MMP group than in the control group. The time interval between the onset and treatment of DG was correlated with PD (rs=0.523, P<0.001) and the rate of positive BOP sites (rs=0.377, P=0.014). Conclusion Patients with DG have obvious periodontal lesions. Early medical intervention is helpful for diag-nosing and treating DG-related oral and systemic disease.