Primate-specific Long Non-coding RNAs and MicroRNAs

摘要

Non-coding RNAs（ncRNAs） are critical regulators of gene expression in essentially all life forms.Long ncRNAs（lncRNAs） and micro RNAs（miRNAs） are two important RNA classes possessing regulatory functions.Up to date,many primate-specific ncRNAs have been identified and investigated.Their expression specificity to primate lineage suggests primate-specific roles.It is thus critical to elucidate the biological significance of primate or even human-specific ncRNAs,and to develop potential ncRNA-based therapeutics.Here,we have summarized the studies regarding regulatory roles of some key primate-specific lncRNAs and miRNAs.