Purpose: To evaluate the therapeutic effect of combind argon and Nd: YAG laser peripheral iridectomy.Methods: 151 cases (200 eyes) of primary angle-closure glaucoma and combined glaucoma were treated by combined procedure. Argon laser was the first used to create partial iridectomy in 2/3-3/4 thickness without penetrating pigmented epithelium, and then Nd: YAG laser was required to complete a patent iridectomy. Results: A successful iridectomy was achieved in all patients independent of any type of irides (100%). Iris penetration rate in one session presented in 95. 0%. Complications appeared to be less common in our patients: iris bleeding was only seen in 5. 0% cases; the postoperative inflammation was mild; corneal burns, lecalized lenticular opacities and closure of iridectomies were less frequent. The follow-up ranged from 3m to 6. 5 years. The success rate in controling IOP with/ without medications were 99. 0% except 2 eyes failur. No attack occured in 129 eyes with prophylatic laser therapy
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