对《中国药典》2010年版磺胺嘧啶锌软膏鉴别试验的探讨

摘要

Objective:To improve the identification test of sulfadiazine zinc ointment in Chinese Pharmacopoeia ( 2010 Edi-tion).Methods: Increasing the sample quantity in the process of potassium ferrocyanide precipitation reaction to filtrate en-richment precipitation and reducing the amount of hydrochloric acid to reduce the total volume of the final solution and to make for the precipitation and enrichment.Results: The improved method can be used to identify sulfadiazine zinc ointment with a high specificity and effectiveness.Conclusion: The improved test method can be listed in the identification test in the sulfadi-azine zinc ointment.%目的：改进《中国药典》2010年版磺胺嘧啶锌软膏鉴别试验方法。方法：增加参与亚铁氰化钾沉淀反应的样品量，可滤过富集沉淀以进行后续的鉴别试验；减少盐酸用量，从而减少最终溶液总体积，更利于沉淀析出和富集。结果：改进后的方法可以专属而有效地鉴别磺胺嘧啶锌软膏。结论：改进后的试验方法可以用于磺胺嘧啶锌软膏的鉴别试验。