Cold stress-regulated immune responses: Insights, challenges, and perspectives

摘要

1 Cold stress reshapes the immune status The winter of 2019 marked history with the advent of the COVID-19 Coronavirus pandemic;Cross-country skiers are more susceptible to asthmatic symptoms than their peers in warmer places[1].The influenza virus causes a more severe infection in winter than in warmer seasons[2].These phenomena suggest that exposure to cold weather increases a person’s vulnerability to health concerns such as the aforementioned“colds”and asthma.While it is accepted that the term“cold”covers a wide array of ailments,it has long been questioned how cold weather brings forth these illnesses.The underlying mechanisms remain to be determined.