Screening of antibacterial activity in marine green, red and brown macroalgae from the western coast of Libya

摘要

Marine macroalgae are considered as an excellent source of bioactive compounds which has a broad range of biological activities including antibacterial and antioxidant. Crude methanolic and water extracts of 19 marine algal species (6 Chlorophyta, 8 Phaeophyta and 5 Rhodophyta) collected from the western coast of Libya were evaluated for antibacterial activity against pathogenic bacteria (4 Gram-positive, 4 Gram-nega- tive). The extracts showed a significant antibacterial activity against Gram positive (Staphylococcus aureus, Bacillus subtilis, Bacillus spp., and Staphylococcus epidermidis) as well as Gram negative bacteria (Escherichia coli, Salmonella typhi, Klebsiella spp., and Pseudomonas aerugi- nosa). The algal aqueous and methanolic extracts displayed different degrees of antimicrobial activities against different bacteria, in some cases methanolic extracts showed higher antibacterial activity than aqueous extracts. Among tested algae, Brown algae namely Cystoseira crinite exhibited the highest antibacterial activity among tested algal species.