The correlations between effects in patients with schizophrenia receiving clozapine：Same root correlation hypothesis

摘要

Objective:To explore the correlations between effects in schizophrenics treated with clozapine.Method:It was estimated for PANSS at baseline and 28th day as well as for serum clozapine level at 29th day in 66 schizophrenics receiving clozapine monotherapy.Results:(1) There was all statistically significant positive correlations between 6 factors of TESS without coincident items;(2) Of 54 correlations between 6 factirs of TESS and 9 subtracting score rates of PANSS subscales.only 6 arrived statistically significant level;(3) of 23 correlations between 9 subtracting score rates of PANSS subscales without coincident items,only 9 were statistically significant.Conclusion:the same root correlation hypothesis in a narrow sense would be utility in future pharmacology.