Since its initial report in 1992,endoscopic ultrasoundguided fine needle aspiration(EUS-FNA) has now been incorporated into the diagnostic and staging algorithm for the evaluation of benign and malignant diseases of the gastrointestinal tract and of adjacent organs.Its introduction constitutes a major breakthrough in the endoscopic field and has gradually transformed EUS from a pure imaging modality into a more interventional procedure.In addition,the possibility of collecting samples,providing a definitive cytological and/or histological evidence of the presence of malignancy,has strongly contributed to changing EUS from a subjective,highly operator dependant procedure into a more objective one.This article will review the instrumentation,technique and the most important clinical applications of EUS-FNA.
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机译:NEW RECOMMENDATIONS FOR THE QUALITY AND SAFETY OF TISSUES AND CELLS FOR CLINICAL APPLICATION AND ITS SIGNIFICANCE FOR THE PRACTICE OF TISSUE ESTABLISHMENTS PERFORMING CRYOPRESERVATION