The plant kingdom is an important potential source of effective treatment for various diseases.Most herbs have long been used for medicinal purposes,and plant metabolites with their derivatives had been used in ethnomedicine.However,concerns exist about the quality and safety of herbal medicine products,particularly relating to safety,dosage,and mechanism of action.This mini review reveals some insights about the Hunteria umbellate seed,which is similar to that of insulin secretagogue metformin.Studies have validated its beneficial role in hyperglycemic,insulin resistance and obesity conditions,which are components of metabolic syndrome.However,none of these studies evaluated the mechanisms by which this plant extract performs its antihyperglycemic,insulin resistance and anti-obesity actions in metabolic syndrome.This understanding would provide considerable progress toward drug design using this plant material.Hence the need for this awareness to sensitize the researchers in this field who are passionate about drug design to consider the pathways discussed below for Hunteria umbellata seeds.Hunteria umbellata seed extract may represent a new therapeutic strategy for type-2 diabetes in place of metformin if it is well-studied.
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