Background: The association of physical activity (PA) and screen time (ST) on health-related quality of life (HRQOL) among predominantly low-income children in the Mississippi Delta region has not been previously described. Methods: We performed a cross-sectional survey to assess health risks from a representative sample of the population ≥3 years old in the Delta Region of Arkansas, Louisiana, and Mississippi. Linear models were utilized to examine Pediatric Quality of Life Inventory (PedsQL) scores based on reported PA and ST. Results: Median age of the 371 participants was 9.8 years, 57% were African American, and 26% had annual household income ≤$14,999. Overall, 262 (75%) were categorized as physically active and 48% reported >2 hours ST per day. Children reporting exercising 5 - 7 days per week had significantly better PedsQL total score (84.3 vs 80.8;p 2 hours per day) did not significantly impact HRQOL. Conclusions: Findings suggest that PA among children living in the Mississippi Delta was related to higher HRQOL;however, the positive effects of PA on HRQOL may be less for minority and low-income children.
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