Clinical Significance of CRP/ALB Ratio in Evaluating the Prognosis of Patients with DLBCL

摘要

Objective: Exploring the expression characteristics of CRP/ALB (CAR) in DLBCL patients and its value in prognostic judgment. Methods: We collected the basic information, clinical characteristics, laboratory examinations and follow-up prognosis of 142 newly diagnosed DLBCL patients with relatively complete data in our hospital and performed statistical analysis. We used X-tile analysis software to obtain the best cut-off value of CAR (0.33), compared the clinical characteristics and survival of patients in the high CAR group and the low CAR group, and compared the survival status with the IPI scoring system. Results: 1) There were significant differences in staging, grouping, IPI scores, extranodal involvement, LDH levels, β2-microglobulin, CA125, and Hb levels between the high CAR group and the low CAR group (all P P Conclusion: High CAR value, like the IPI scoring system, is an independent poor prognostic factor of DLBCL, can be used as a reliable indicator of prognosis. And CAR can also be combined with IPI to evaluate the prognosis of DLBCL, of which the effect is better than that of IPI alone.