Intracranial Venous and Mesenteric Vein Thrombosis in a Case of Lung Cancer with Brain, Bone, and Leptomeningeal Metastasis

摘要

Cancer patients with venous thromboembolism (VTE) are not rare, and the second death cause in patients with cancer is VTE. Although VTE itself is associated with reduced survival particularly in cancer patients, many oncologists may not place enough importance in positive prevention of VTE. Here, we report the case of a 38-year-old male lung cancer patient with brain, bone and leptomeningeal metastasis who diagnosed as a consequential intracranial venous and mesenteric vein thrombosis. The evolution of headache has not been noted gradually, from which led to the underestimation of headache and without careful consideration on the possibility of suspected intracranial venous thrombosis. The problem of mesenteric vein thrombosis reflects the dilemma resulted from the potential risk of thrombogenesis and the high risk of hemorrhage. Preventive anticoagulation strategies are key means especially in patients with cancer, and the management problems of this condition are discussed.