Effect of Egyptian Date Palm Pollen (Phoenix dactylifera L.) and Its Hydroethanolic Extracts on Serum Glucose and Lipid Profiles in Induced Diabetic Rats

Manal M. Abdel-Shaheed; Eveleen S. Abdalla; Ayman F. Khalil; Eshak M. El-Hadidy

摘要

Diabetes is a major health global problem that has reached alarming levels. The present study aims for studying the effect of date palm pollen (Phoenix dactylifera L.) El-Hayani cultivar on serum glucose and lipids profile in induced diabetic male albino rats. Palm pollen chemically analyzed besides chemical constituents, mineral contents, polyphenols and flavonoids. Male Albino rats (36 rats weight 170-190 style="font-family:Verdana;">gm) were divided style="font-family:Verdana;">in style="font-family:Verdana;">to style="font-family:Verdana;"> 6 groups. 1 style="font-family:Verdana;">: style="font-family:Verdana;">Normal control ( style="font-family:Verdana;">- style="font-family:Verdana;">), 2 style="font-family:Verdana;">: style="font-family:Verdana;"> Alloxanized diabetes control (+) (150 style="font-family:;" "=""> style="font-family:Verdana;">mg/Kg rat body weight). Diabetic groups 3 and 4 had 0.5%, style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">1.0% date palm pollen, respectively, also diabetic style="font-family:Verdana;">group style="font-family:Verdana;">s style="font-family:Verdana;"> 5 and 6 had 100 ppm, 200 ppm date palm pollen extract, respectively. At the end of style="font-family:Verdana;">the style="font-family:Verdana;">experiment style="font-family:;" "=""> style="font-family:Verdana;"> (4 weeks) rats were fasted overnight and anesthetized and blood samples were taken for analysis of serum glucose, lipids profile style="font-family:Verdana;">and style="font-family:Verdana;"> renal-hepatic function parameters, relative organ weight data obtained are style="font-family:Verdana;">statistically style="font-family:Verdana;"> analysis. Results showed that the major polyphenolic components were that e-vanillic acid (16.33 mg/100 style="font-family:;" "=""> style="font-family:Verdana;">g), pyrogallol (15.02 mg/100 style="font-family:;" "=""> style="font-family:Verdana;">g), epicatechin (11.04 mg/100 style="font-family:;" "=""> style="font-family:Verdana;">g), catechin (10.96 mg/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">g). style="font-family:Verdana;">While, style="font-family:Verdana;"> date palm pollen was rich in hesperidin (8.84 mg/100 style="font-family:;" "=""> style="font-family:Verdana;">g), Kaempferol 3 style="font-family:Verdana;">, style="font-family:Verdana;">2 p-coumaroyl glucose (6.92 mg/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">g), style="font-family:Verdana;">hesperitin style="font-family:Verdana;"> (5.10 mg/100 style="font-family:;" "=""> style="font-family:Verdana;">g), rutin (3.11mg/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">g) as flavonoids components. Date palm pollen has style="font-family:Verdana;">high style="font-family:Verdana;"> content of protein, calcium style="font-family:Verdana;">and style="font-family:Verdana;"> iron (30.87 g/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">g, 510.82 style="font-family:Verdana;">and style="font-family:Verdana;"> 236.50 mg/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">g), respectively. Also, serum glucose decreased significantly in diabetic groups (3, 4, 5 style="font-family:Verdana;">and style="font-family:Verdana;"> 6, respectively) (179.47, 137.80, 156.77, 145.47 mg/100 style="font-family:;" "=""> style="font-family:;" "=""> style="font-family:Verdana;">mL, respectively). Lipids profile, renal and liver functions were improved style="font-family:Verdana;">significant style="font-family:Verdana;">ly style="font-family:;" "=""> style="font-family:Verdana;"> (P < 0.05) in diabetic groups style="font-family:Verdana;">which had style="font-family:Verdana;"> date palm pollen or its extracts.> style="font-family:Verdana;">It is concluded that the dried date palm pollen 1% in the diet and 200 ppm extract are more effective compared with controlling diabete

机译：糖尿病是一个达到惊人的全球问题的主要卫生问题。本研究旨在研究日期棕榈花粉（Phoenix Dactylifera L.）El-Hayani品种在诱导的糖尿病雄性白化大鼠血清葡萄糖和脂质型材上的效果。除了化学成分，矿物质含量，多酚和黄酮外，棕榈花粉化学分析。雄性白化大鼠（36只大鼠重量170-190 style =“font-family：Verdana;”> gm）被分开样式=“font-family：verdana;”> < / span> style =“font-family：verdana;”>到 style =“font-family：verdana;”> 6组。 1 style =“font-family：verdana;”>： style =“font-family：verdana;”>正常控制（ style =“字体 - 家庭：Verdana;“> - style =”font-family：verdana;“>），2 style =”font-family：verdana;“>： < Span Style =“Font-Family：Verdana;”>异种糖尿病控制（+）（150 style =“font-womain :;”“=”> style =“字体-Family：Verdana;“> Mg / kg大鼠体重）。糖尿病组3和4具有0.5％， <跨度样式=”字体家族：“”=“> style =“font-womain :;” “=”“> <跨度样式=”font-family：verdana;“> 1.0％date palm pollen，也分别糖尿病患者 style =”font-family：verdana;“> group style =“font-family：verdana;”> s style =“font-family：verdana;”> 5和6分别有100 ppm，200 ppm棕榈花粉提取物。在 y =“font-family：verdana;”> y style =“font-family：verdana;”>实验 style =“字体家族:;“”=“”> <跨度样式=“Font-Family：Verdana;”>（4周）大鼠禁食过夜，进行麻醉和血液样品进行分析，用于分析血清葡萄糖，脂质分布 style =“font-family：verdana;”>和 style =“font-family：verdana;”>肾肝功能参数，获得的相对器官重量数据 style =“font-family：verdana;”>统计上 style =“font-family：verdana;”>分析。结果表明，主要的多酚组分是e-香草酸（16.33mg / 100 style =“font-womain :;”“=”> style = “Font-Family：Verdana;”> G），Pyrogallol（15.02 mg / 100 style =“font-womain :;”“=”> style =“font-family ：Verdana;“> g），EpicateChin（11.04 mg / 100 style =”font-family :;“”=“> style =”font-family：verdana;“ > g），儿茶（10.96 mg / 100 style =“font-gryse :;”“=”> style =“font-family :;”“=”“> style =“font-family：verdana;”> g）。 style =“font-family：verdana;”>虽然， style =“font-family：verdana; “>枣棕榈花粉在橙皮素富含含量（8.84 mg / 100 style =”font-womain :;“”=“> style =”font-family ：Verdana;“> G），Kaempferol 3 样式=”font-family：verdana;“>， style =”font-family：verdana;“> 2 p-coumaroyl葡萄糖（6.92 mg / 100 style =“font-family :;”“=”“> style =”font-family :;“”=“” > style =“font-family：verdana;”> g）， style =“font-family：verdana;”> Hesperitin style =“font-family：verdana; “>（5.10 mg / 100 style =”font-family :;“”=“”> style =“font-family：verdana;”> g），rutin（3.11mg / 100 style =“font-grysion :;”“=”> style =“font-gryse :;”“=”“> <跨度样式=“Font-Family：Verdana;”> g）作为类黄酮组成部分。枣椰子花粉具有 style =“font-family：verdana;”> high style =“font-family：verdana;”>蛋白质，钙的含量style =“font-family：verdana;”>和 style =“font-family：verdana;”>铁（30.87 g / 100 style =“font-家庭：“”=“”> style =“font-gryse :;”“=”“> style =”font-family：verdana;“> g，510.82 < Span Style =“font-family：verdana;”>和 style =“font-family：verdana;”> 236.50 mg / 100 style =“font-family ：“”=“”> 样式=“font-family :;”“=”“> style =”font-family：verdana;“> g）。此外，血清葡萄糖在糖尿病组中显着降低（3,4,5 <跨度=“Font-Family：Verdana;”>和 6，分别为6）（179.47,137.80,156.77,145.47 mg / 100 style =“font-family :;”“=”“> style =”font-家庭：“”=“”> <跨度样式=“Font-Family：Verdana;”> ml，分别）。脂质剖面，肾和肝功能得到改善 <跨度样式=“font-family：verdana;”>重要的 style =“font-family：verdana;”> ly < / span> style =“font-womain :;” “=”“> <跨度样式=”font-family：verdana;“>（p <0.05）在糖尿病组中 style =”font-family：verdana;“>其中 <跨度样式=“font-family：verdana;”>日期棕榈花粉或其提取物。 > style =“font-family：verdana;”>结束了与控制糖尿病相比，饮食中干燥的日期棕榈花粉1％更有效

Effect of Egyptian Date Palm Pollen (Phoenix dactylifera L.) and Its Hydroethanolic Extracts on Serum Glucose and Lipid Profiles in Induced Diabetic Rats

摘要

著录项

相关主题

期刊订阅