Hidden stage of intracranial hemorrhage in newborn rats studied with laser speckle contrast imaging and wavelets

摘要

Using the laser speckle contrast imaging and wavelet-based analyses,we investigate a latent("hidden")stage of the development of intracranial hemorrhages(ICHs)in newborn rats.We apply two measures based on the continuous wavelet-transform of blood flow velocity in the sagittal sinus,namely,the spectral energy in distinct frequency ranges and a multiscality degree characterizing complexity of experimental data.We show that the wavelet-based multifractal formalism reveals changes in the cerebrovascular blood flow at the development of ICH.