Objective To discuss the clinical value of percutaneous biliary drainage operation in severe liver obstructive cholangitis. Methods 72 patients with severe obstructive cholangitis were selected as the research group and were randomly divided into control and treatment groups, who underwent open common bile duct decompression surgery and percutaneous transhepatic bili-ary drainage. According to operation time, drainage time and time to get out of bed after operation, serum bilirubin levels and the incidence rate of complications were compared to determine the value of the two groups. Results The patients'operation time, drai-ning time, the time to get out of bed and postoperative serum bilirubin levels were compared with statistically significant difference (P<0. 05) in the two groups. Postoperative complications rate in treatment group was 36. 1% (13/36), significantly lower than the 55. 5% (22/36) in the control group, with significant difference between the two groups (P<0. 05). Conclusion Compared to the control group treated with the traditional open surgical decompression in terms of common bile duct, the treatment group treated with per-cutaneous biliary drainage has less postoperative complications, and the operation is easy to perform and clinical outcome is satisfactory.%目的：探讨经皮肝胆管引流术对肝内梗阻性重症胆管炎的治疗效果。方法以72例梗阻性重症胆管炎为研究对象，依计算器法随机分为对照组和治疗组，每组各36例，分别行开放式胆总管切开减压术和经皮肝胆管引流术。根据手术时间、引流时间、术后下床时间、术后血清胆红素水平及并发症发生情况等比较两组的治疗效果。结果治疗组与对照组手术时间及引流时间、术后下床时间、血清胆红素水平，组间比较差异均有统计学意义(P<0．05)。术后并发症发生率对照组、治疗组分别为55.5%(22/36)、36.1%(13/36)，组间比较差异有统计学意义(P<0．05)。结论相较于传统开腹胆总管切开减压术，经皮肝胆管引流术治疗肝内梗阻性重症胆管炎术后并发症少，操作方便，临床效果显著。
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