卡前列素氨丁三醇预防孕产妇产后出血的临床效果观察

摘要

Objective To explore the effect and adverse reactions of carboprost tromethamine in preventing maternal postpartum hemorrhage. Methods 100 full-term pregnant women undergoing lower uterine segment cesarean section in our hospital from May 2013 to May 2015 were randomly divided into two groups, with 50 cases in each group. The experimental group was given uterus intramuscular injection of carboprost tromethamine, the control group was given uterus intramuscular injection of oxytocin. All patients received conventional nursing after operation. The bleeding volume during and after operation were calculated by capacity calculation method and weighing method. The dynamic Hb and RBC were monitored. Results The bleeding volume during operation of two groups had no statistical difference (P>0.05), but the bleeding volume, Hb and RBC decrease value after 2 h, 24 h of the operation of experimental group were lower than those of control group (P<0.05). The incidence of adverse reactions of two groups had no statistical difference (P>0.05). Conclusions Carboprost tromethamine has certain curative effect in preventing maternal postpartum hemorrhage, and has lower adverse reactions and certain application advantages, which can relieve the postoperative reaction and deserve clinical application.%目的：探讨卡前列素氨丁三醇预防孕产妇产后出血的临床效果及不良反应。方法选取我院2013年5月至2015年5月收治的100例足月欲行子宫下段剖腹产的住院孕产妇，随机分为两组各50例。实验组在剖腹产后行卡前列素氨丁三醇子宫肌注射，对照组行缩宫素子宫肌注射。所有患者术后行常规护理，并通过容量计算法和称重法计算患者术中和术后出血量，同时监控患者动态Hb、 RBC值。结果两组术中出血量比较差异不显著(P＞0.05)，但实验组术后2 h、24 h出血量和Hb及RBC的下降值均小于对照组(P＜0.05)。两组不良反应发生率相比差异不显著(P＞0.05)。结论卡前列素氨丁三醇在预防孕产妇产后出血上具有一定临床效果，其不良反应较低，可减轻患者术后反应及不适，在临床应用中有一定的应用优势，值得临床推广。