目的 探讨血清降钙素原(PCT)及C-反应蛋白(CRP)在判断肺炎患者病情严重程度及评估预后方面的价值.方法 选择2010年1月至2011年2月就诊于重庆市合川区人民医院及重庆医科大学附属第二医院呼吸内科门诊及住院的社区获得性肺炎(CAP)患者62例为治疗组,治疗组分别按CAP的严重程度又分为3组,1组(n=21)不具备建议住院的危险因素;2组(n=22)符合住院标准的CAP,即具备一项或一项以上建议住院的危险因素,但是不够诊断重症肺炎的标准;3组(n=19)重症肺炎,即符合诊断重症肺炎的标准.随机抽取同期健康体检者28例为对照组.比较各组患者治疗后的血清PCT、CRP水平.结果 治疗1、2、3组患者的PCT、CRP水平高于健康对照组(P＜0.05).结论 检测血清PCT、CRP浓度有助于判断肺炎严重程度.%To investigate the value of serum procalcitonin(PCT) and C-reactive protein(CRP) for estimation of severity and prognosis in the patients with community acquired pneumonia(CAP). Methods 62 patients with CAP admitted to our hospital from January 2010 to February 2011 were selected as the treatment group. The treatment group was subdivided into 3 subgroups according to the severity of CAP. The group l(n = 21) had no risk factors of hospitalization suggested by the national standards, the group 2(n = 22) was accorded with the hospitalization standard,possessing the above hospitalization risk factors ≥1, but not reaching the diagnostic standard of severe pneumonia, and the group 3(n= 19) was accorded with the standard of severe pneumonia. Meanwhile, 28 healthy individuals were randomly extracted as controls. Serum PCT and CRP after treatment were measured and compared among the four groups. Results Serum PCT and CRP levels in the treatment group 1,2 and 3 were higher than those in the healthy control group (P<0. 05). Conclusion Detecting serum PCT and CRP could be useful for assessment of the severity of pneumonia.
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