Objective To explore the influence of life quality for the breast cancer patients receiving chemotherapy after the cog-nitive ,behavioral and psychological intervention to their spouse .Methods 120 breast cancer patients received standardized chemo-therapy and their spouses ,and divided into control and intervention groups .The intervention group receive the routine care and health guidance .Before and after chemotherapy ,the life quality of patients was investigated .The data was analyzed statistically .Re-sults The result by the breast cancer patients Quality of Life Questionnaire in Chinese (FACT-B) show that ,the scores of the con-trol and intervention groups in the physiological status ,social/family status ,emotional status ,functional status ,additional attention andtotalscorewere(18.77±4.18,16.48±4.60,17.35±4.41,16.04±4.80,20.81±6.02,89.45±6.34 ;22.46±3.57,19.03± 4 .83 ,18 .58 ± 3 .96 ,18 .59 ± 4 .48 ,24 .73 ± 5 .63 ,103 .39 ± 8 .91) .The scores of intervention groups was increased significantly than the control group .The data was analyzed statistically .Conclusion The quality of life of patients was improved by the cognitive ,be-havioral and psychological guidance and intervention to the spouse of breast cancer chemotherapy patients.%目的：探讨对乳腺癌化疗患者的配偶进行认知、行为和心理干预后，对乳腺癌化疗患者的生命质量的影响。方法选择120例接受标准化化疗的乳腺癌患者及其配偶，分为对照组和干预组，对干预组进行相关的指导和干预，在化疗前、后对患者生命质量进行测定，并进行统计学分析。结果乳腺癌患者生命质量测定量表中文版（FACT-B）测定的结果表明，化疗后对照组和干预组患者在生理状况、社会/家庭状况、情感状况、功能状况、附加关注和总分分别为（18．77±4．18，16．48±4．60，17．35±4．41，16．04±4．80，20．81±6．02，89．45±6．34；22．46±3．57，19．03±4．83，18．58±3．96，18．59±4．48，24．73±5．63，103．39±8．91），干预组得分有显著提高，两组比较差异有统计学意义。结论对乳腺癌化疗患者的配偶进行认知、行为和心理的指导、干预，有利于提高患者的生命质量。
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