An urea adsorbent with an aldo structure was obtained by the oxidation of a crosslinked β-cyclodextrin polymer. The highest urea adsorption capacity reached 56. 7mg/g in 0. 05Maqwueous phosphate buffer 37℃ and pH = 7. 4, and decrease to 4. 8mg/g in aqueous human serum albumin. The composite adsorbent was prepared by the oxidation of a crosslinked β-cyclodextrin and dialytic membrane. It was found that the composite adsorbent has a higher urea adsorption selectivity and capacity compared to that of the oxidation of a crosslinked β - cyclodextrin adsorbent when urea is in aqueous human serum albumin.
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