＜正＞ Background Acute kidney injury （AKI） is associated with poor prognosis after cardiopulmonary bypass. The aim of thisretrospective study was to investigate whether stent implantation before cardiopulmonary bypass has beneficial effect ondevelopment of AKI in renal artery stenosis （RAS） patients.Methods In this retrospective study, patients with abnormal baseline serum creatinine （SCr, ＞106 μmol/L） were notincluded. Included patients （n=69） were divided into two groups. Group 1 included 31 RAS patients receiving no stentimplantation before cardiopulmonary bypass. Group 2 included 38 RAS patients having received stent implantation justbefore cardiopulmonary bypass. To assess AKI after cardiopulmonary bypass, serum urea nitrogen, SCr and creatinineclearance were recorded at baseline, at the end of operation, during the first and second postoperative 24 hours.Results Baseline characteristics were similar between groups. Serum urea nitrogen, SCr, creatinine clearance beforeand after cardiopulmonary bypass were also similar class groups. Incidence of AKI in group 1 was not significantlydifferent from group 2. In group 1, AKI defined by RIFLE between occurred in 7 （22.6%） patients: 5 （16.1%） with RIFLE-R,2 （6.5%） with RIFLE-I, and no patients with RIFLE-F. In group 2, 10 patients （26.3%） had an episode of AKI duringhospitalization: 6 （15.8%） had RIFLE-R, 4 （10.5%） had RIFLE-I, and no patients had RIFLE-F.Conclusions There are no data suggesting that it is necessary to stent RAS patients with normal SCr before cardiopulmonarybypass. However, it cannot be concluded that RAS is not associated with AKI after cardiopulmonary bypass.
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