HLA-DRB1 alleles genotyping in patients with rheumatoid arthritis in Chinese.

摘要

Objective: To explore the role of HLA-DRB₁ genes in the development of rheumatoid arthritis （RA） and the correlations between HLA-DR alleles and clinical manifestations of patients with RA. Methods: 86 patients and 106 race matched controls in whom HLADR typing was performed by the method of DNA amplification with sequence-specific primers （PCR-SSP）