Clinical analysis of protionamide and para-aminosalicylic acid induced hepatotoxicity in 129 cases

摘要

Objective To investigate drug-induced liver injury (DILI) in tuberculosis (TB) patients treated with protionamide (Pto) and (or) para-aminosalicylic acid (PAS) ,and therefore to provide data for using secondline anti-tuberculosis drugs and risk prediction of liver damage.Methods A retrospective analysis was performed for TB patients treated with regimens containing