Gene-targeted radiation therapy mediated by radiation-sensitive promoter in lung adenocarcinoma and the feasibility of micro-PET / CT in evaluation of therapeutic effectiveness in small animals

摘要

Objective To explore the combined anti-tumor effect of radiation therapy and gene-targeted suppression of tumor neovasculature in lung adenocarcinoma in vivo,and to explore the feasibility of micro-PET/CT in dynamic evaluation of treatment effectiveness.Methods Thirty5-6 week old male BALB/c nude mice were used in this study.The mouse models of xenotransplanted human