The effects of excessive iodine intake on mRNA expressions of interleukin-23,interleukin-17 and gamma interferon in BABL/c mice

摘要

Objective To observe the effects of excessive iodine intake on autoimmune thyroiditis and mRNA expressions of interleukin-17(IL-17),interleukin-23(IL-23)and gamma interferon(IFN-γ)in thyroid gland and spleen of mice and to further explore the pathogenesis of iodine overdose induced autoimmune thyroiditis.Methods According to body mass,seven to eight weeks old BALB/c mice(body mass 20-25 g,half male and half female)were selected and divided into 4 groups(12 mice in each