Objective To study the development pattern of fetal facial angle during pregnancy, and the application of fetal facial angle measurement in diagnosing micrognathia in prenatal. Methods 188 normal fetuses in 20-36 gestational weeks were select, the fetal facial angle were measured with three-dimensional ultrasound, The range of normal values of fetal facial angle was analysed using SPSS 13. 0 software. Person correlation coefficient (r) was used to assess the correlation between fetal facial angle and the gestational weeks i the difference of fetal facial angle were contrast between micrognathia and normal group. Results There was negativecorrelation between the normal fetal facial angle and the gestational weeks(r=0. 001 ,P = 0. 757). Average value of the normal fetal facial angle is 62. 37°,SD 6. 23°,fetal facial angle less than 49. 9° was diagnosed micrognathia. The 6 micrognathia fetal facial angle were all less than 49. 9°. Conclusions Detection of the fetal facial angle with three dimensional ultrasound was an objective quantitative detection method for diagnosis micrognathia in prenatal.%目的 研究胎儿颜面部角度孕期发育规律,探讨测量胎儿颜面部角度在产前诊断小下颌畸形中的应用价值.方法 选择20～36孕周正常胎儿188例,应用经腹三维超声测量胎儿颜面部角度,采用SPSS 13.0软件分析颜面部角度正常值范围,Person相关系数(r)评估胎儿颜面部角度与孕周相关性;对比小下颌畸形胎儿颜面部角度与正常组差异.结果 20～36孕周正常胎儿颜面部角度与孕周无相关性,r=0.001,P=0.757.胎儿颜面部角度均值是62.37°,标准差为6.23°.颜面部角度小于49.9°诊断为小下颌畸形.6例小下颌畸形胎儿颜面部角度均小于49.9°.结论 应用三维超声检测胎儿颜面部角度,为产前诊断小下颌畸形提供一种客观定量的检测方法.
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