微电极引导苍白球腹后侧毁损术治疗帕金森病震颤

摘要

目的探讨微电极引导苍白球毁损术对帕金森病震颤的治疗效果，为震颤型帕金病外科手术方法的选择提供依据。方法79例震颤型帕金森病患者进行了苍白球毁损术，治疗前及治疗后3个月采用VAS(Visual Analog Scale)对患者震颤严重程度进行评估。结果 79例患者震颤显著改善68例(86.1％)，在包含震颤同步细胞68例中，震颤显著改善62例(91.2％)，P＜0.05，有统计学意义。结论微电极引导苍白球腹后侧毁损术对帕金森病震颤有很好的疗效。%Objective To analyze the effect of microelectrode guided posteroventral pailidotomy on parkinsonian tremor and ascertain the way of surgery to treat parkinsonian tremor. Method 79 patients with parkinsonian tremor underwent microelectrode-guided posteroventral pallidotomy. Tremor severity was measured on a patient-rated. 100mm Visual Analog Scale(VAS), both preoperatively and 3 months postoperatively. Result Tremor was improved by 50% in 68 patients(86.1%) and 62 patients(91.2%)of 68 patients in whom tremor-synchronous cell were recorded. This difference was significant(P＜0.05). Conclusion After pallidotomy, tremor had been greatly improved.