Synthesis and Crystal Structure of 5,17-Diformyl-11,23-di(tert-butyl)-25,26,27,28-tetrapropoxy-calix4arene

摘要

The title compound 5,17-diformyl-11,23-di(tert-butyl)-25,26,27,28-tetrapropoxycalix[4]arene has been synthesized by selective formylation of 5,11,17,23-tetra(tert-butyl)25,26,27,28-tetrahydroxycalix[4]arene in three steps and characterized by1H NMR and X-ray single-crystal diffraction.The crystal belongs to the monoclinic system,space group C2/c with a = 25.760(3),b = 10.9952(10),c = 18.630(2),β = 119.985(4)°,V = 4570.4(9)3,Z = 4,Dc = 1.106 g/cm3,Mr = 761.01,F(000) = 1648,μ = 0.071 mm-1,MoKa radiation(λ = 0.71073),R = 0.0710 and wR = 0.2411 for 3234 observed reflections with I > 2σ(I).X-ray analysis reveals that the title compound adopts a pinched cone conformation which leads to an open cavity.Intermolecular C-H O weak interactions link the molecules along the bc plane,which are effective in the stabilization of the crystal structure.