Objective: To explore the effectiveness of manual lymphatic drainage technology (MLDT) combined with Xuehai (SP10) and Yanglingquan (GB34) acupoint-pressing treating lower limbs swelling after soft tissue trauma. Methods: Eighty Wistar rats were randomly divided into normal, model, MLDT and combined treatment groups, with 8 rats in normal group, and 24 rats in the rest groups. Soft tissue trauma model was made in model, MLDT and combined treatment groups. Rats in MLDT group were treated by MLDT, and those in combined treatment group were treated by MLDT combined with acupoint-pressing treatment. Normal and model groups got not treatment. Volume-measuring method was applied to observe the foot swelling degree before and at 1st, 3rd, and 7th day after treatment. ELSIA was used to detect the expression of serum TNF-ct. Results: At the 1st day after treatment, there were significant differences in TNF-α among groups (P<0. 05) , the foot volume result revealed T group 展开▼