基于LifeMOD的个性化人工膝关节设计中的生物力学分析

摘要

Objective: To investigate the biomechanical performanre of individualized design artificial knee joint after surgical operation.Method: Based on the digital biomechanical simulation software LifeMOD, human biomechanical model for simulating the motions of healthy human and total knee replacement(TKR) patient in normal gait was designed and generated, where the motion and internal forces could be explored.Result: The outputs included joint angles, joint contact forces and ligament / muscle forces. Through comparative analysis, the individualized artificial knee joint could replicate the normal knee ideally in gait characteristics.Conclusion: This study provided an effective access for further research of dynamic knee biomechanics, as well as a reference to artificial knee joint design, performance evaluation and clinical application.%目的:探讨个性化设计的人工膝关节植入人体后的生物力学响应.方法:基于生物力学数字仿真软件LifeMOD,建立健康人体及人工膝关节置换术后人体步行的运动/动力学模型,对人体在步行过程中的运动和内部受力情况进行分析.结果:仿真得到整个步态周期中膝关节的运动的角位移、关节接触力以及韧带和肌肉的载荷曲线,通过对比分析,可知本文所设计的人工膝关节在步态特性方面较理想地复制了正常的膝关节.结论:本研究对探索人工膝关节的动态生物力学特性和关节似体的设计、性能评价以及临床应用等有重要意义.