超声测量胎儿胸腺在母体妊娠期高血压综合征的应用

摘要

目的：通过超声测量合并母体孕期高血压综合征的胎儿胸腺横径和前后径，评估胎儿胸腺发育和妊娠母体高血压综合征之间的相关性。方法选取2012年12月～2013年12月于本院临床诊断为妊娠高血压综合征孕妇30例归入观察组，同时随机选取100例 18-40周孕妇归入对照组，取两组胎儿三血管切面胸腺横径、前后径测值，对照组参数行线性回归分析，两组胎儿胸腺横径、前后径均值分别行t 检验，以 P ＜0．05为具有显著差异性。结果对照组胎儿胸腺横径和孕周回归方程为Y ＝0．139X －1．173，R 2＝0．796，P ＜0．05；对照组胎儿胸腺前后径和孕周回归方程为Y ＝0．49X －0．176，R 2＝0．813， P ＜0．05，两组参数胎儿胸腺横径、前后径均值分别行 t 检验，P ＜0．05。结论胎儿胸腺超声测值在母体合并妊娠期高血压综合征时小于相应孕周正常妊娠胎儿胸腺测值95％置信区间，胎儿胸腺发育和母体妊娠期高血压综合征具相关性。%Objective Measure the transverse diameter,the anteroposterior diameter of fetal thymus through ultrasound,to assess the correlation between fetal thymus development and hypertension syn-drome of pregnancy.Method 30 cases of patients diagnosed as hypertension syndrome of pregnancy in our hospital from December 2012 to December 2013 were put into the observation group,while 100 cases were selected into the control group randomly.The transverse diameter and the anteroposterior diameter were measured in the three vessel view,The control parameters were analyzed by linear regression analysis, mean of two groups parameters were tested by t test respectively,P <0.05 was considered significant. Results The regression equation of fetal thymus transverse diameter and GA is:Y =0.139X -1 .173,R2=0.796,P <0.05 ;the regression equation of fetal thymus anteroposterior diameter and GA is :Y =0.49X-0.176,R2 =0.813,P <0.05 ;Mean of two groups t test get P <0.05 .Conclusions Fetuses whose mother are accompanied with hypertension syndrome of pregnancy ,their thymus measurement are less than those of the same GA fetal thymus measurement,there are correlation between fetal thymus develop-ment and hypertension syndrome of pregnancy.