This paper reviews clinical observations on 142 pediatric cases of infectious diseases and its relation with complement C_3 and immunologlobulin. During the infectious stage, C_3displayed a change opposite to that of leukocyies due to C_3's participating in the adjustment of immunity. C_3, hemoglobin and hepatic funotion were consistent with one another in their relationship. There was a general increase in Ig during the infection, mainly IgM and IgG. IgM had an early increase followed by a quick abation. Their increase occurred in the order of IgM, G, and A. A nortonl or raised value of C_3 indicates the restorage of the patient's resistence and a better prognosis. A chronic lower value of C_3 is a sign of weaker resistence or a tendency for the infection to become chronic and relapse. Therefore, the authors hold that the understanding of the regularity of the changes of C_3 is of clinical significance in the prevention of infections.%@@ 大连医学院附属一院小儿外科佟大永机体抗病能力与免疫机制有着密切关系.补体与免疫球蛋白(Ig)在抗感染反应中是不可缺的介质和效应物.二者都是血清中一组球蛋白.
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