光学相干断层扫描血管造影在青光眼中的应用

摘要

光学相干断层扫描血管造影(OCTA)是一种全新的、非侵入性的成像系统,可产生视网膜、脉络膜层的结构数据,显示结构和血液流动信息.分频幅去相关血管成像(SSADA)算法(OCTA的一个重要组成部分)有助于降低信噪比,通过运动对比使视网膜血管成像更清晰,从而为治疗提供更加有意义的图像及数据,是眼科检测方法的一个重大突破.目前对于青光眼缺乏有效的早期诊断方法.OCTA的出现使得血流动力学可以作为评价青光眼的指标.现将对这项新的无创性检查方法在闭角型青光眼、开角型青光眼、正常眼压性青光眼这三种类型的青光眼临床上的应用进行综述.%Optical coherence tomography angiography (OCTA) is a new, non-invasive imaging system, can produce the structure data of retina and choroid, shows the structure and blood flow information. Split-spectrum amplitude-decorrelation angiography (SSADA) algorithman (an important part of OCTA) can help reduce the signal-to-noise ratio, enhancing visualization of retinal vasculature using motion contrast. OCTA can provide more meaningful image data for the treatment which is a major breakthrough in the eye detection method. Currently there is lack of effective early diagnosis methods for glaucoma. OCTA as a parameter, can evaluate the structural parameters of glaucoma. This article will review the application of this new non-invasive method in the clinical application of three types of glaucoma: Angle-closure glaucoma, open angle glaucoma and normal tension glaucoma.