Objective In order to evaluate the stability of intraocular lens after Nd∶YAG laser capsulotomy with the assessments of anterior chamber depth, intraocular lens (IOL) tilt and decentration. Methods In this prospective study , total 29 patients ( 35 eyes ) enrolled in from March 2013 to September 2014 in Eye Hospital of Wenzhou Medical University. Preoperatively and postoperatively, routine examinations including uncorrected visual acuity (UCVA), best corrected visual acuity (BCVA), intraocular pressure (IOP), slit lamp microscope examination of anterior segment, and fundus examination were taken, meanwhile, the assessments of the anterior chamber depth, IOL tilt and decentration by rebuilding three-dimensional model of anterior segment swept-source optical coherence tomography (AS-SSOCT) were evaluated. All these data were analyzed using paired t test and rank sum test. Results BCVA of this 35 eyes was improved from (0.57 ±0.34)logMAR preoperatively to (0.15 ± 0.15)logMAR 1 month postoperatively (t=7.753, P<0.01). There was no significant statistical differences among the IOP variation. Anterior chamber depth was (4.15±0.37)mm preoperatively and (4.16±0.39)mm 1 month postoperatively . Preoperative and 1 month postoperative IOL tilt in x orientation was -0.099°(-0.840°~0.057°) and -0.125°(-0.757°~0.067°), IOL tilt in y orientation was -0.015°(-0.564°~0.113°) and -0.014°(-0.210°~0.155°), IOL decentration in x orientation was 0.051 (-0.066~0.192)mm and 0 . 049 (-0 . 038~0 . 127 ) mm , IOL decentration in y orientation was 0 . 111 ( 0 . 009~0 . 204 ) mm and 0.106(0.013~0.194)mm; the differences were without statistical significance. Conclusion Nd∶YAG laser capsulotomy is effective and safe to treat posterior capsule opacification, BCVA improve postoperatively, the position of IOL is stable postoperatively, and postoperative anterior chamber depth, intraocular tilt and decentration have not siginificant changed.%目的：通过检测Nd∶YAG激光后囊膜切开术前与术后前房深度、人工晶状体（IOL）倾斜度和偏心量的变化，评估其对IOL稳定性的影响。方法前瞻性研究。纳入2013年3月至2014年9月在温州医科大学附属眼视光医院行Nd∶YAG激光后囊切开术的符合入选标准的后发性白内障患者29例（35眼）。术前及术后1个月予以常规眼科检查[包括裸眼视力（UCVA）、最佳矫正视力（BCVA）、眼压（IOP）、眼前段及眼底检查]，并利用眼前节扫频光源相干断层扫描结合Matlab图像分析软件对眼前节进行三维重建，测量前房深度及IOL在x轴（水平方向）和y轴（垂直方向）的倾斜度和偏心量。应用配对样本t检验和符号秩和检验对BCVA、IOP、前房深度及IOL倾斜度和偏心量做相应的统计学分析。结果 BCVA从术前的0.57±0.34（logMAR）提高到术后1个月的0.15±0.15（logMAR），差异有统计学意义（t=7.753，P<0.01）。术前、术后IOP的差异无统计学意义。术前前房深度为（4.15±0.37）mm，术后1个月为（4.16±0.39）mm，差异无统计学意义。术前、术后1个月IOL在x轴的倾斜度分别为-0.099°（-0.840°～0.057°）和-0.125°（-0.757°～0.067°），在 y 轴的倾斜度分别为-0.015°（-0.564°～0.113°）和-0.014°（-0.210°～0.155°），在x轴的偏心量分别为0.051（-0.066～0.192）mm和0.049（-0.038～0.127）mm，在y轴的偏心量分别为0.111（0.009～0.204）mm和0.106（0.013～0.194）mm，差异均无统计学意义。结论Nd：YAG激光后囊膜切开术是治疗后发性白内障安全有效的方法，术后视力显著提高，IOL稳定，前房深度、IOL的倾斜度和偏心量均无明显改变。
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