首页> 中文期刊> 《中国现代药物应用》 >利用尿微量蛋白评估和诊断慢性心力衰竭初期心肾综合征患者的临床价值

利用尿微量蛋白评估和诊断慢性心力衰竭初期心肾综合征患者的临床价值

         

摘要

目的:近30%的慢性心力衰竭(CHF)患者合并心肾综合征,且临床疗效不佳;选择一种早期检测方法尤为必要。方法临床回顾观察120例CHF 患者,其中84例为非心肾综合征为观察组2、36例心肾综合征患者为观察组1,观察尿微量蛋白、肌酐与正常人群之间的差别。结果观察组1 NYHA IV TRF为(11.75±4.13)mg/L,观察组2 NYHA IV TRF为(3.79±3.26)mg/L,对照组为(2.03±0.37)mg/L。结论利用尿微量蛋白预判心肾综合征较为敏感,对临床诊断、治疗本病有着重要意义。%Objective Around 30%chronic heart failure(CHF) patients with cardiorenal syndrome with poor clinical treatment efficacy, it is necessary to find an early diagnostic method. Methods Retrospectively analyzing 120 patients with CHF and dividing them into observation group(group 1) and 2 based on the absence and presence of cardiorenal syndrome, respectively. Levels of urine trace protein and creatinine were determined in these two groups and compared with those of healthy populations. Results NYHA IV TRF in observational group 1, observational group 2 and control group were (11.75±4.13)mg/L, (3.79±3.26)mg/L and (2.03±0.37)mg/L, respectively. Conclusion Urine trace protein is a sensitive indicator for the diagnosis of cardiorenal syndrome which has great significance in the diagnosis and treatment of this disease.

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