肠易激综合征(Irritable Bowel Syndrome,IBS)是一种较常见的功能性肠道疾病,也是一种典型的心身性疾病.发病特征为慢性、反复发作的腹部疼痛或不适,并伴随有排便异常等肠道功能紊乱性症候群.临床表现为腹痛、腹泻,大便急迫不尽感,便秘或便秘与腹泻交替、腹胀、肠鸣及矢气等.长期的久治不愈,严重影响患者的生存质量和身心健康.IBS患者以20～40岁中青年居多,男女比例为1∶2.目前我国尚未进行有关IBS的大规模流行病学调查,但亦相当常见,有的地区IBS患者约占消化门诊病人的1/3[1],且已成为临床难治疾病之一.%Objective: To observe effects of EA Tianshu point, Zusanli point on the irritable bowel syndrome rat models to discuss a part of the mechanism of IBS' s acu-puncture treatment. Method: To divide the young VISTAR rats into normal group, model group, Tianshu group and Zusanli group, six per group. The Tianshu group and Zusanli group were started to be given EA in the 6th week, once two days ,a total of seven times. Model group was bounded but not given EA. The normal group was done nothing. To use XW-B-3 cold lightmicro-circulation tester to observe the rats' state of caps and blood flow of mesentery microcirculation in each group and different time period. Results; (l)The estimate of the visceral sensitivity.- compared with the normal group, the value of the model group rats' belly raising and back hunch-up significantly reduced (P*C0. 01). Compared with the model group, the value of the EA Tianshu and Zusanli group rats' belly raising and back hunch-up significantly increased (P<0. 01). (2)Test of the mesentery microcirculation. (Dthe diameter of the blood vessel: compared with the normal group, the diameter of the mesentery micro-vessels of the mode! Group significantly narrowed (P<0. 05); Compared to the model group, the diameter of the mesentery micro-vessels of the EA Tianshu group and Zusanli group significantly expanded(P<0. 05 or P<0. 01). ?The state of the blood flow., compared with the normal group, the model group's blood flow speed of mesentery micro-vessels significantly reduced or stopped (P<0. 01). Conclusion: EA Tianshu. Zusanli can significantly increase the value of the visceral sensitivity threshold of the IBS rats and reduce the visceral sensitivity; it can also significantly improve the blood state of the mesentery microcirculation and remove spasm to relieve the lack of blood and oxygen in the intestinal mucosa. As a result, it has the therapeutic effect of pain relief.
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