116例骨巨细胞瘤手术患者的临床特点及疗效分析

摘要

Objective To analyze the clinical characteristics and surgical treatment of 116 patients with giant cell tumor of bone.Method Retrospective analysis of a total of 116 cases with giant cell tumor of bone, which were diagnosed by histopathology from Sichuan Luzhou traditional Chinese medicine hospital and the affiliated hospital of Southwestern Medical university,from 2009 January to 2014 December, including 44 cases of male, 72 cases of female. The average age was 36.5 years old between 11 to 66 years old.The incidence of long bone was 94 cases, while 22 cases located in flat or short bone.All patients were treated with primary surgery.Result The ratio of male to female was 1:1.6 of the116 patients with giant cell tumor of bone. The high incidence was from 31 to 40 years old.The overall recurrence rate was 28% (32/113) of the113 patients following up for 1.5 to 7.5 years. The 30 cases were treated with reoperation, while 2 cases were treated with radiotherapy or chemotherapy of the 32 cases with recurrence.Conclusion The incidence of giant cell tumor of bone was easier to relapse after surgery of the young and middle-aged women.It is an important method to reduce the recurrence rate with using extensive curettage and adjuvant method.%目的 探讨骨巨细胞瘤患者的临床特点及手术治疗效果.方法 回顾性分析2009年1月至2014年12月在泸州市中医医院及西南医科大学附属医院就诊并经组织病理学确诊的骨巨细胞瘤患者共116例.其中男44例,女72例;年龄11~66岁,平均36.5岁;发病部位位于长骨94例,扁骨或短骨22例.均为初次手术治疗患者.结果 116例骨巨细胞瘤患者中,男女比例为1:1.6;发病主要以31~40岁年龄段居多;本组手术治疗后113例患者获连续随访,随访时间1.5~7.5年,整体复发率为28%(32/113).术后复发32例,30例行再次手术治疗,2例行放、化疗.结论 骨巨细胞瘤发病以中青年女性为多且术后易复发,正确使用广泛刮除术配合辅助方法是降低其复发率的重要手段.