图像处理工具箱测定卵泡的形态参数

摘要

目的:数字图像处理被广泛的应用在生物医学领域,并取得一些成果,但对卵泡形态参数进行测量的系统报道不多.本文研究利用计算机图像处理技术,对促排卵治疗患者的卵泡形态参数进行测量,在生殖医学的临床诊断方面有重要的现实意义和广阔的应用前景.方法:使用The MathWorks公司的MATLAB软件中的图像处理工具箱(image pro-eessing toolbox)编写程序.先将获取的原始卵泡图像先进行四步预处理:一、提取原始图像,二、估计背景亮度,三、调整背景,四、调整对比度;然后再进行四步图像分割:一、提取图片,二、图像二值化,三、面积围封,四、确定边界.最后对得到所需样本.测量卵泡面积、周长、最大直径、等效圆直径、似圆度五个形态参数.结果:测出比较理想的卵泡的面积、周长、最大直径、等效圆直径、似圆度五个形态参数.结论:应用图像处理工具箱(image processing toolbox)可对卵泡形态参数的实现简便的测量.%Objective: Digital images processing is widely applied in the fields of biology and medicine, and some achievements have been gained by this technique. But there is few reports on measure the parameters of morphology of pathology from the patients which were threated by ovulation induction, by computer processing techniques. The work shows it has significant value in clinical diagnosis and reproductive medicine at present and in the future. Methods: Write the programmeces by Image Processing Toolbox in MATLAB. The original pathology images are preprocessed by 4 steps: step 1: read imagejstep 2: imopen the curve background brightness; step 3: adjust the background; step 4: adjust the contrast. Then segmentation image by 4 steps; step 1: read image; step 2: estimation the image; step 3: remove the noise; step 4: find the boundaries. The end, measure the parameters of morphology. Results: The pathology was studied percase for their area, perimeter, maximum diameter, equivalent diameter and metric. Conclusions: Image Processing Toolbox is useful to measure the parameters of morphology of pathology.