应用超短回波MRI技术综合定量评价骨皮质质量

摘要

骨矿物质密度是当前评价骨物理性质的金标准,但多项临床研究已经证明此方法的缺陷.由于常规MRI不能探测到骨的信号,故不能评价骨的质量.近年来提出的超短回波(UTE)序列可以直接得到骨及其周围组织的图像,并可以定量得到骨皮质的T1、T2*及骨灌注值.这为定量评估骨质量提供了新方法.本文将对UTE-MRI及其在骨皮质定量评价中的应用现状进行综述.%Current guidelines utilize bone mineral density (BMD) as a gold standard for assessment of the mechanical properties of bone. However, many clinical studies have demonstrated the limitation of BMD. Conventional clinical MRI cannot detect the signal of bone. In recent years, ultrashort echo time (UTE) sequences were proposed to directly image bone and adjacent tissues, in order to obtain T2, T2* and bone perfusion value, which providing a new way to quantitative assess the quality of bone. The recent research progresses of quantitative UTE-MRI and its clinical application in quantitative evaluation of cortical bone were reviewed in this article.