首页> 中文期刊> 《中国介入心脏病学杂志》 >侧支循环对ST段抬高急性心肌梗死再灌注治疗后心功能的影响

侧支循环对ST段抬高急性心肌梗死再灌注治疗后心功能的影响

             

摘要

Objective To determine whether the presence of coronary collateral lfow, as evidenced by angiography, has a beneifcial effect on left ventricular function in ST-segment-elevation myocardial infarction (STEMI) treated by means of early percutaneous coronary intervention (PCI). Methods Between April 2012 to November 2013, 95 patients with STEMI treated with primary PCI successfully were analyzed. According to the Rentrop grade, these patients were divided into 2 groups:collateral circulation group (n=16) and non-collateral circulation group (n=79). The left ventricular function was evaluated within 24 hours after PCI and 30 days later. Results Comparison of 2 groups showed that collateral lfow was associated with better left ventricular ejection fraction within 24 hours and 30 days after PCI. And non-collateral lfwa was associated with more ventricular aneurysm formation. Conclusions The presence of angiographically detectable collaterals has a protective effect on left ventricular function in ST-segment-elevation myocardial infarction (STEMI) treated by primary PCI.%目的:评价冠状动脉侧支循环对于ST段抬高急性心肌梗死(STEMI)患者急诊经皮冠状动脉介入治疗(PCI)后心功能的影响。方法纳入2012年4月至2013年11月在北京安贞医院急诊科行急诊PCI的STEMI患者95例,入院后均急诊行冠状动脉造影,并行急诊介入治疗,成功开通罪犯血管。根据冠状动脉造影结果按Rentrop方法评价侧支循环情况,分为有侧支循环组(16例)和无侧支循环组(79例)。分别于术后24 h内和术后30 d应用超声心动图评价心功能情况。结果 PCI术后24 h内,有侧支循环组的左室射血分数明显高于无侧支循环组[(53.4±7.1)%比(47.1±8.4)%,P<0.05];有侧支循环组出现室壁瘤的比例低于无侧支循环组,但是差异无统计学意义[3例(18.8%)比29例(36.7%),P>0.05]。门诊随访术后30 d,有8例患者出现失访,均为无侧支循环组;超声结果显示,有侧支循环组的左心室射血分数依然明显高于无侧支循环组[(56.3±6.9)%比(49.5±8.9)%,P<0.05];体表心脏超声显示有侧支循环组出现室壁瘤的比例明显低于无侧支循环组[3例(18.8%)比36例(50.7%),P<0.05]。结论早期开放的侧支循环对于STEMI急诊PCI后患者的心功能具有保护作用。

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