益气健脾汤联合针刺治疗气虚型帕金森病病人便秘的临床疗效

摘要

Objective To investigate the effect of Yiqi Jianpi decoction (YJD) and acupuncture in the treatment of constipation in patients with Parkinson's disease (PD) and qi deficiency syndrome.Methods Seventy PD patients with constipation and qi deficiency syndrome were randomly divided into two groups:control group (n =34) treated with lactulose,and treatment group (n =36) treated with YJD and acupuncture for 8 weeks.The clinical efficacy and the scores of traditional Chinese medicine (TCM) symptom were observed.Results After 8 weeks of treatment,the total effective rate after two months was 77.78％ in treatment group and 55.88％ in control group (P ＜0.05).The scores of TCM symptom were decreased in two groups after 8 weeks of treatment (P ＜0.05 or P ＜0.01).The scores of TCM symptom were decreased in two groups after 2 months of treatment (P ＜0.05 or P ＜0.01).Conclusion YJD and acupuncture has better short-term and long-term clinical efficacy in PD patients with constipation and qi deficiency syndrome.%目的 观察益气健脾汤联合针刺治疗气虚型帕金森病病人便秘的临床疗效.方法 选择气虚型帕金森病便秘病人70例,随机分为治疗组(n=36)与对照组(n=34).治疗组给予益气健脾汤,每日1剂、每日2次口服,结合针刺取穴,隔日1次;对照组予乳果糖口服液(杜秘克),每日3次,每次10 g,餐后30 min口服,疗程均为8周.观察两组治疗前后的临床疗效,并记录两组治疗前后症状积分变化.结果 治疗组远期疗效总有效率为77.78％,对照组为55.88％,两组比较差异有统计学意义(P＜0.05);治疗8周后,两组病人症状总积分及各项症状积分均较治疗前明显降低(P ＜0.05或P＜0.01);两组治疗结束后2个月症状总积分及各项症状积分均较治疗前明显降低(P ＜0.05或P＜0.01).结论 以益气健脾联汤合针刺治疗气虚型帕金森病病人便秘r具有较好的近期及远期临床疗效,其停药后的远期疗效更具有优势.