A Synoptical Introduction of The Clinical Application of Tripterygium Glycosides

摘要

Tripterygium glycosides (TG) refers to the total glycosides, mainly the epoxy diterpene lactones extracted from the root of Tripterygium Wilfordii Hook f (TW), a common vine-like toxic plant grown in the wide area of South China. It possesses potent anti-inflammatory and immune suppressive effects and also some anti-coagulation and bacteriocidal action, and compared with other preparations of TW, it shows the superiority of being small in dose and having less adverse effect. It has been reported to be effective in treating patients with such diseases as rheumatoid arthritis, lupus or purpura nephritis, psoriasis, erythroderma, and allergoses. This article is attended to synoptically introduce the recent clinical applications of TG.