Objective To observe the influence of Hewei Anshen Tang on quality of sleep and life of patients with insomnia. Methods A prospective and self-control clinical trial was carried out. Fifty-two patients with insomnia were collected and treated with Hewei Anshen Tang. PSQI and WHOQOL-BREF scores of patients were assessed and sleep phases were monitored by MSMSMS before and after treatment. Results After treatment of Hewei Anshen Tang, the total score of PSQI and scores of five items, including sleep quality, sleep time, total sleep time, sleep efficiency, daytime dysfunction, were decreased (P＜0.01). Sleep latency and awakening time were decreased, deep sleep time and REM sleep time were increased detected by MSMSMS (P＜0.05 or 0.01). WHOQOL-BREF scores in physiological, psychological and social fields were increased (P＜0.05 or 0.01). Conclusions Hewei Anshen Tang can regulate sleep pattern, improve the quality of sleep and life of patients with insomnia.%目的 观察和胃安神汤对失眠症患者睡眠及生活质量的影响.方法 采用前瞻性、自身对照方法,以匹兹堡睡眠质量指数量表(PSQI)、世界卫生组织生活质量测定量表简表(WHOQOL-BREF)、微动敏感床垫睡眠监测系统(MSMSMS)为研究工具,观察52例失眠症患者服用和胃安神汤前后睡眠及生活质量变化情况.结果 和胃安神汤可以降低患者PSQI总分以及睡眠质量、入睡时间、睡眠时间、睡眠效率、日间功能障碍评分(P<0.01);缩短患者入睡潜伏期、觉醒时间,增加患者深睡眠时间和REM睡眠时间(P<0.05或0.01);提高患者WHOQOL-BREF生理、心理、社会领域评分(P<0.05或0.01).结论 和胃安神汤可以调整失眠症患者的睡眠结构,改善其睡眠质量以及生活质量.
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