麒麟丸联合'三采嬉戏'疗法治疗肾气不固型继发性早泄临床研究

摘要

目的 观察麒麟丸联合"三采嬉戏"疗法治疗肾气不固型继发性早泄(APE)的临床疗效.方法 将129例肾气不固型APE患者随机分为中药组、房中术组、联合组各43例.中药组予麒麟丸,每次6 g,每日3次,口服.房中术组指导患者性交时行"三采嬉戏"疗法,平均每周性交≥2次.联合组予麒麟丸联合"三采嬉戏"疗法,方法同上.均连续治疗8周.观察治疗前,治疗4、8周及治疗后4周射精潜伏期(IELT)、中国早泄患者性功能评价表(PECI-5)评分、中医症状评分.结果 与治疗前比较,3组治疗后不同时点IELT均提高(P<0.05).联合组治疗后不同时点(除与中药组治疗4周比较)IELT均优于其他2组(P<0.05).与治疗前比较,3组治疗后不同时点PECI-5评分均改善(除房中术组治疗4周的Q6、Q7),差异有统计学意义(P<0.05).联合组治疗8周及治疗后4周PECI-5中Q5、Q6、Q7评分改善水平明显优于其他2组(P<0.05).与治疗前比较,中药组、联合组治疗后各时点中医症状评分均明显改善(P<0.05);房中术组入房早泄、性欲减退评分明显改善(P<0.05),精神萎靡、动则自汗治疗8周及治疗后4周明显改善(P<0.05).联合组治疗8周及治疗后4周中医症状评分改善水平明显优于其他2组(P<0.05).结论 麒麟丸联合"三采嬉戏"疗法治疗肾气不固型APE疗效确切、持久.%Objective To observe clinical efficacy of Qilin Pills combined with Three-Spot Caressing in the treatment of acquired non-consolidated kidney qi premature ejaculation (PE). Methods Totally 129 acquired non-consolidated kidney qi PE patients were randomly divided into TCM group, Fangzhognshu group and combination group. TCM group was given Qilin Pills, 6 g each time, three times a day, orally. Fangzhognshu group was guided to conduct Three-spot Caressing during sexual intercourse, no less than twice a week. Combination group was given Qilin Pills and Three-spot Caressing with the same method as Fangzhognshu group. The treatment course for each group lasted for 8 weeks. Before and after treatment of 4 weeks, 8 weeks and 4 weeks after with drawal, the intravaginal ejaculatory latency time (IELT), Chinese Index of Sexual Function for Premature Ejaculation-5 (PECI-5) scores and TCM syndrome scores (TCMS) were compared. Results Compared with before treatment, IELT increased in three groups at different time points after treatment (P<0.05). In the combination group, IELT was superior to the other two groups (except for TCM group after 4-week treatment), with statistical significance (P<0.05). Compared with before treatment, PECI-5 scores improved in three groups (except for Q6 and Q7 in Fangzhongshu group after 4-week treatment) at different time point after treatment (P<0.05). The improvement of Q5, Q6 and Q7 scores in PECI-5 of combination group was significantly better than that in the other two groups at 8-week treatment and 4-week after treatment (P<0.05). Compared with before treatment, TCMS in TCM group and combination group were improved significantly (P<0.05), PE and loss of libido score improved significantly in Fangzhongshu group (P<0.05);mental malaise and move spontaneous perspiration were significantly improved at 8-week treatment and 4 weeks after treatment (P<0.05). The improvement in TCMS was significantly better in combination group than that in the other two groups at 8-week treatment and 4 weeks after treatment (P<0.05). Conclusion Qilin Pills combined with Three-Spot Caressing has definite and long-term efficay for the treatment of acquired non-consolidated kidney qi PE.