目的 观察柴朴汤治疗慢性咳嗽的临床疗效.方法 纳入191例慢性咳嗽柴朴汤方证患者,开展多中心临床观察.给予柴朴汤颗粒剂,每日1剂,早晚分服,共服7~14剂.于治疗前及治疗1、2周填写中医证候积分量表,观察中医疗效和中医症状改善情况.结果 治疗1、2周的有效率分别为84.3%(161/191)、97.9%(187/191).治疗2周的咳嗽消失率为67.01%(128/191);除咽痒、咽中物堵外,单项症状有效率均>90%,其中寒热往来、胸闷、呕恶、心烦、胁痛有效率位居前列,分别为98.8%、97.9%、97.9%、97.2%、96.6%.结论 柴朴汤对慢性咳嗽柴朴汤方证患者有良好治疗效果.%Objective To study the efficacy of Chaipo Decoction on chronic cough.Methods Totally 191 patients with chronic cough treated with Chaipo Decoction syndrome were included to conduct multi-center clinical observation. The patients were given Chaipo Decoction Granules, 1 dose each day, morning and night, 7-14 doses in total. TCM syndrome integral scales were filled before treatment and 1 week and 2 weeks after treatment to observe TCM efficacy and TCM symptom improvement.Results After 1 and 2 week of treatment, the total effective rate was 84.3% (161/191), 97.9% (187/191), and disappearance rate of cough was 67.01% (128/191). Except for pharyngeal itching and pharynx material block, the effective rate of single symptom >90%, among which the effective rates of cold and heat, chest tightness, vomitting, upset, and hypochondriac pain were in the forefront, 98.8%, 97.9%, 97.9%, 97.2%, and 96.6%, respectively.Conclusion Chaipo Decoction has good efficacy for treatment of chronic cough.
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