Objective To explore the relations between variation in content of plasma D-dimer, fibrinogen in patients of cerebral infarction and occurrence of cerebral infarction and clinical significance of that. Methods Plasma D-dimer, fibrinogen content of 40 patients with cerebral infarction and 31 controls was determined. Results Compared with control,plasma D-dimer content of cerebral infarction patients was higher(P＜0.01),fibrinogen(Fbg) level rose significantly(P＜0.01). Conclusion Plasma D-dimer has close relationship with the occurrence and development of cerebral infarction. The increase of plasma Fbg level is an important risk factor of cerebrovascular disease. The increase of Fbg is closely related with the occurrence and development of cardio-cerebral vascular diseases.%目的 探讨脑梗死患者血浆中D-二聚体、纤维蛋白原含量(Fbg)变化与脑梗死发生的关系及其临床意义.方法 测定40例脑梗死患者及31 例对照者血浆D-二聚体、Fbg含量.结果 与对照组相比,脑梗死患者血浆D-二聚体含量、Fbg水平显著增高(均P< 0.01).结论 血浆中的D-二聚体与脑梗死的发生、发展有密切关系;血浆Fbg水平的升高是脑血管病的重要危险因素,Fbg的增高与脑血管病变的发生发展密切相关.
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