水囊扩张法与地诺前列酮栓用于足月妊娠引产的疗效、安全及经济性比较研究

摘要

Objective:To evaluate the effect,safety and economy of water balloon dilation compared with dinoprostone suppositories for inducing labor of full-term pregnancy.Methods:120 women with full-term pregnancy were divided into study group and control group.The women in study group were treated by water balloon dilation for induced labor,and the women in control group were treated by dinoprostone suppositories for induced labor.The cervical Bishop score of women in both groups were evaluated before treatment,and at 4 hours,12 hours and 24 hours after treatment.Delivery situation of all women and state of neonate,such as neonatal Apgar score,birth weight,rate of amniotic fluid pollution and fetal distress were all recorded.Results:The cervical Bishop scores of women in both groups after treatment were significant increased than those of women before treatment (P ＜ 0.05).There were no significant difference in the cervical Bishop score of women between the two groups at 4 hours,12 hours and 24 hours after treatment (P＞0.05).Postpartum hemorrhage volume,oxytocin dosage and vaginal delivery rate of women had no statistical significant between the two groups (P＞0.05).The time of treatment to delivery and time of total labor of women in study group were significant shorter than those of women in control group (P＜0.05),and the cost of treatment of women in study group was also significant lower than that of women in control group (P＜0.05).There were no significant difference in neonatal Apgar score,neonatal weight,rate of amniotic fluid contamination Ⅱ-Ⅲ degrees,and rate of fetal distress between the two groups (P＞0.05).Conclusion:Comparing to dinoprostone suppositories for inducing labor of full-term pregnancy,water balloon dilation has better efficacy,safety and economic.%目的:探讨水囊扩张法与地诺前列酮栓用于足月妊娠引产的疗效、安全及经济性对比研究.方法:将本院择期引产的120例足月妊娠孕妇分别采用水囊扩张法或地诺前列酮栓干预,于干预前及干预后4h、12h、24h,对两组孕妇进行宫颈Bishop评分并记录分娩情况和新生儿状态.结果:两组宫颈Bishop评分干预后均较干预前升高(P＜0.05),但两组间干预后4h、12h、24h评分比较无差异(P＞0.05);两组产后出血量、缩宫素用量、阴道分娩等比较无差异(P＞0.05);采用水囊扩张法组的用药至临产时间、总产程及治疗费用均优于地诺前列酮栓组(P＜0.05);而两组的新生儿Apgar评分、新生儿体重、羊水污染Ⅱ～Ⅲ度、胎儿窘迫未见差异(P＞0.05).结论:水囊扩张法与地诺前列酮栓用于足月妊娠引产均具有较好的疗效及安全性,水囊扩张法的经济性更优.